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The Dangers of Artificial Sweeteners

Updated: Aug 30, 2021

Some of you may now be wondering about sweeteners such as Splenda®, Nutra Sweet®, or Equal®. Perhaps you’re thinking of switching to these sugar-free alternatives now that I’ve vilified sugar. But, hold on for just a minute. My advice is to stay far (FAR) away from these too. The reasons are many, but I’ll list a few important ones.


Let’s start with Aspartame (NutraSweet® and Equal®). Aspartame is the most widely used sweetener in the world. It has zero calories and tastes 200 times sweeter than sugar, but it breaks down into phenylalanine and aspartic acid (which act as neurotoxins when absorbed too quickly). It also breaks down into methanol (which is wood alcohol found in antifreeze) and is then oxidized into formaldehyde in various tissues. Yes, formaldehyde… you know, the fluid that morticians use for embalming. Yummy.

Studies show aspartame causes migraines, especially in youth (16), but this is just one of the more than 90 reported side effects! It also affects DNA (especially in the mitochondria), damages the structure of the sciatic nerve, (17) causes weight gain, (18) and neurophysiological symptoms such as learning difficulty, seizures, migraines, irritable moods, anxiety, depression, and insomnia. (19)

Aspartame is hard to avoid, though, because it’s found in more than 6000 products–things like “diet” foods, frozen desserts, gelatins, puddings, fillings, nutrition bars, chewing gum, soda, powdered soft drinks, tabletop sweeteners, and yogurt. Even sugar-free pharmaceuticals like cough drops contain aspartame. The only way to avoid it is to read labels and eat real food.


Now let’s talk about Splenda, aka Sucralose. Sucralose is said to be 600 times sweeter than table sugar without the calories. The claim is that sucralose comes from sugar, so it’s a more natural non-calorie sweetener—and yes, it does start from a sugar (sucrose) molecule. But then three chlorine molecules are added to the sugar molecule (yes, chlorine). This changes the chemical structure drastically. In fact, Dr. Mercola says, chemically, “Splenda is actually more similar to DDT than sugar.” (20)

The Architect did not design the temple of the human body to use a “sugar” like this. It is not properly metabolized. This is evident through recent studies which show sucralose consumption leads to increased insulin secretion, elevated glucose levels, reduced glucagon secretion, delayed gastric emptying, altered sweet taste receptors, a 50% reduction in good gut flora, induced DNA damage, and increased risk for weight gain as well as the development of diabetes. (21)

What’s more, cooking with sucralose at high temperatures can generate chloropropanols, a potentially toxic class of compounds. (21)

Plain and simple, it’s advisable to stay far away from saccharin, aspartame, sucralose, acesulfame K, and neotame.

High Fructose Corn Syrup

I would be remiss if I didn’t also talk about another harmful sweetener called high fructose corn syrup. High Fructose Corn Syrup (and “corn syrup”) are synthetic food ingredients. Like other artificial sweeteners, the temple of the body does not know what to do with these or how to digest them. This form of fructose can confuse the brain, affect hunger hormones, and increase appetite. (22)

Research also shows a connection between high fructose corn syrup and disrupted stress hormones, fat accumulation, reduced glucose tolerance, insulin resistance, higher triglycerides, and cholesterol, (23) and increased blood pressure. (24) High doses of free fructose have even been proven to punch holes in the intestinal lining. (25)

What’s more, it’s been reported that nearly half of all tested samples of commercial high-fructose corn syrup contained mercury. (24) In fact, some estimate it contains up to 570 micrograms of mercury per gram.

Again, if you want to avoid this sweetener (which you should), you’re going to have to be diligent and read labels as you shop.

Safe Sweeteners

So now the big question is, what sweeteners ARE safe? My top two recommendations are Stevia and Monk Fruit. Stevia is a very sweet herb (200 times sweeter than sugar) that does not raise blood glucose levels. However, it is part of the ragweed family and can be problematic for those with a ragweed allergy. Also, some powdered forms of Stevia can undergo processing, such as bleaching. They also may have added ingredients such as maltodextrin (from corn), so it is important to choose a reputable brand that is non-GMO verified.

Another, and perhaps even better sweetener, is monk fruit. Monk fruit contains a significant amount of antioxidants to fight free radicals; it is 300-400 times sweeter than sugar but does not have any calories or effect on blood sugar levels. It also acts as an antihistamine and is anti-inflammatory. Monk fruit is also sold in liquid and powder form.